Asahara Lab
Systems BioMedicine
Ito Y, Inoue A, Seers T, Hato Y, Igarashi A, Toyama T, Taganov K, Boldin M, Asahara H*. Identification of targets of tumor suppressor microRNA-34a using a reporter library system. Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3927-3932.
Nakasuji T, Ogonuki N, Chiba T, Kato T, Shiozawa K, Yamatoya K, Tanaka H, Kondo T, Miyado K, Miyasaka N, Kubota T, Ogura A, Asahara H*. Complementary critical functions of Zfy1 and Zfy2 in mouse spermatogenesis and reproductiontran. PLoS Genetics. 2017 Jan 23;13(1):e1006578.
Koda N, Sato T, Shinohara M, Ichinose S, Ito Y, Nakamichi R, Kayama T, Kataoka K, Suzuki H, Moriyama K, Asahara H*. Mohawk transcription factor regulates homeostasis of the periodontal ligament. Development. 2017 Jan 15;144(2):313-320.
Ito Y, Matsuzaki T, Ayabe F, Mokuda S, Kurimoto R, Matsushima T, Mochizuki Y, Inotsume M, Tsutsumi H, Liu L, Shinohara M, Tanaka Y, Nakamichi R, Nishida K, Lotz M, Asahara H*. Both microRNA-455-5p and -3p repress hypoxia-inducible factor-2α expression and coordinately regulate cartilage homeostasis. Nat Commun. provisionally accepted.
Kurimoto R, Chiba T, Ito Y, Matsushima T, Yano Y, Miyata K, Yashiro Y, Suzuki T, Tomita K, Asahara H*. The tRNA pseudouridine synthase TruB1 regulates the maturation and function of let-7 miRNA. EMBO J. 2020 e104708.
Sato T, Kataoka K, Ito Y, Yokoyama S, Inui M, Mori M, Takahashi S, Akita K, Takada S, Ueno-Kudoh H, Asahara H*. Lin28a/let-7 Pathway Modulates the Hox Code via Polycomb Regulation during Axial Patterning in Vertebrates. eLife. 2020 May 29;9:e53608.
Mokuda S, Nakamichi R, Matsuzaki T, Ito Y, Sato T, Miyata K, Inui M, Olmer M, Sugiyama E, Lotz M, Asahara H*. Wwp2 maintains cartilage homeostasis through regulation of Adamts5. Nat Commun. 2019 Jun 3;10(1):2429.
Mitsumura T#, Ito Y#, Chiba T#, Matsushima T, Kurimoto R, Tanaka Y, Kato T, Uchida K, Ito T, Yamamoto K, Eishi Y, Kitagawa M, Miyazaki Y, Inase N, Asahara H*. Ablation of miR-146b in mice causes hematopoietic malignancy. Blood Adv. 2018 Dec 11;2(23):3483-3491.
Mochizuki Y, Chiba T, Kataoka K, Yamashita S, Sato T, Kato T, Takahashi K, Miyamoto T, Kitazawa M, Hatta T, Natsume T, Takai S, Asahara H*. Combinatorial CRISPR/Cas9-approach to elucidate a far-upstream enhancer complex for tissue-specific Sox9 expression. Dev Cell. 2018 Sep 24;46(6):794-806.
Inui M*, Mokuda S, Sato T, Tamano M, Takada S, Asahara H*. Dissecting the roles of miR-140 and its host gene. Nat Cell Biol. 2018 May;20(5):516-518.
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