​

         2012 - 1995
 

​  2012

1. Yamashita S, Miyaki S, Kato Y, Yokoyama S, Sato T, Barrionuevo F, Akiyama H, Scherer G, Takada S, Asahara H*. L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity. J Biol Chem. 2012 Jun 22;287(26):22206-15.

2. Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H*. Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26.
   ------------Review

3. Miyaki S, Asahara H*. Macro view of microRNA function in osteoarthritis. Nat Rev Rheumatol. 2012 Sep;8(9):543-52. Review.

4. Yamashita S, Asahara H*. miRNA Functions in Arthritis. Current Rheumatology Reviews. 2012, 8, 98-102

5. Ito Y, Kayama T, Asahara H*. A systems approach and skeletal myogenesis. Comp Funct Genomics. 2012;2012:759407. Review.

6. Takada S, Asahara H*. Current strategies for microRNA research. Mod Rheumatol. 2012 Sep;22(5):645-53. Review.
   ---------------------------Collaboration

7. Fukami M, Tsuchiya T, Takada S, Kanbara A, Asahara H, Igarashi A, Kamiyama Y, Nishimura G, Ogata T. Complex genomic rearrangement in the SOX9 5' region in a patient with Pierre Robin sequence and hypoplastic left scapula. Am J Med Genet A. 2012 Jul;158A(7):1529-34.

8. Chan EF, Harjanto R, Asahara H, Inoue N, Masuda K, Bugbee WD, Firestein GS, Hosalkar HS, Lotz MK, Sah RL. Structural and functional maturation of distal femoral cartilage and bone during postnatal development and growth in humans and mice. Orthop Clin North Am. 2012 Apr;43(2):173-85. Review.
   
    2011

9. Asada M#, Rauch A#, Shimizu H, Maruyama H, Miyaki S, Shibamori M, Kawasome H, Ishiyama H, Tuckermann J, Asahara H*. DNA binding-dependent glucocorticoid receptor activity promotes adipogenesis via Krüppel-like factor 15 gene expression.  Lab Invest. 2011 Feb;91(2):203-15.. 
   --------------Review

10. Asahara H*. Switching gears to an arthritis gene expression network by SirT1 cleavage. Arthritis Rheum. 2011 Aug;63(8):2161-3. Review.

11. Yokoyama S, Asahara H*. The myogenic transcriptional network.Cell Mol Life Sci. 2011 Jun;68(11):1843-9. Review.
    ---------------------------Collaboration

12. Wada S, Kato Y, Okutsu M, Miyaki S, Suzuki K, Yan Z, Schiaffino S, Asahara H, Ushida T, Akimoto T. Translational suppression of atrophic regulators by microRNA-23a integrates resistance to skeletal muscle atrophy. J Biol Chem. 2011 Nov 4;286(44):38456-6.

13. Awazawa M, Ueki K, Inabe K, Yamauchi T, Kubota N, Kaneko K, Kobayashi M, Iwane A, Sasako T, Okazaki Y, Ohsugi M, Takamoto I, Yamashita S, Asahara H, Akira S, Kasuga M, Kadowaki T. Adiponectin enhances insulin sensitivity by increasing hepatic IRS-2 expression via a macrophage-derived IL-6-dependent pathway. Cell Metab. 2011 Apr 6;13(4):401-12.

14. Mizutani R, Nakamura K, Yokoyama S, Sanbe A, Kusakawa S, Miyamoto Y, Torii T, Asahara H , Okado H, Yamauchi J, Tanoue A. Developmental expression of sorting nexin 3 in the mouse central nervous system.Gene Expr Patterns. 2011 Jan-Feb;11(1-2):33-40.
    
     2010

15. Miyaki S, Sato T, Inoue A, Otsuki S, Ito Y, Yokoyama S, Kato Y, Takemoto F, Nakasa T, Yamashita S, Takada S, Lotz MK, Ueno-Kudo H, Asahara H*. MicroRNA-140 plays dual roles in both cartilage development and homeostasis. Genes Dev. 2010 Jun 1;24(11):1173-85

16. Ito Y, Toriuchi N, Yoshitaka T, Ueno-Kudoh H, Sato T, Yokoyama S, Nishida K, Akimoto T, Takahashi M, Miyaki S, Asahara H*. The Mohawk homeobox gene is a critical regulator of tendon differentiation. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10538-42

17. Higashiyama R, Miyaki S, Yamashita S, Yoshitaka T, Lindman G, Ito Y, Sasho T, Takahashi K, Lotz M, Asahara H*.Correlation between MMP-13 and HDAC7 expression in human knee osteoarthritis. Mod Rheumatol. 2010 Feb;20(1):11-7. 
    --------------Review

18. Furumatsu T*, Asahara H*.  Histone acetylation influences the activity of Sox9-related transcriptional complex. Acta Med Okayama.2010 Dec;64(6):351-7. Review.
    ---------------------------Collaboration

19. Otsuki S, Hanson SR, Miyaki S, Grogan SP, Kinoshita M, Asahara H, Wong CH, Lotz MK. Extracellular sulfatases support cartilage homeostasis by regulating BMP and FGF signaling pathways. Proc Natl Acad Sci U S A. 2010 Jun 1;107(22):10202-7. 

20. Otsuki S, Grogan SP, Miyaki S, Kinoshita M, Asahara H, Lotz MK. Tissue neogenesis and STRO-1 expression in immature and mature articular cartilage. J Orthop Res. 2010 Jan;28(1):96-102. 

21. Nakanishi K, Nakasa T, Tanaka N, Ishikawa M, Yamada K, Yamasaki K, Kamei N, Izumi B, Adachi N, Miyaki S, Asahara H, Ochi M. Responses of microRNAs 124a and 223 following spinal cord injury in mice. Spinal Cord. 2010 Mar;48(3):192-6.
    
    2009

22. Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M,  Asahara H*. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48.

23. Ito T, Yadav N, Lee J, Furumatsu T, Yamashita S, Yoshida K, Taniguchi N, Hashimoto M, Tsuchiya M, Ozaki T, Lotz M, Bedford MT,  Asahara H*. Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC Dev Biol. 2009 Sep 2;9:47.

24. Miyaki S, Nakasa T, Otsuki S, Grogan SP, Higashiyama R, Inoue A, Kato Y, Sato T, Lotz MK,  Asahara H*. MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses. Arthritis Rheum. 2009 Sep;60(9):2723-30.

25. Yamashita S, Andoh M, Ueno-Kudoh H, Sato T, Miyaki S, Asahara H*. Sox9 directly promotes Bapx1 gene expression to repress Runx2 in chondrocytes. Exp Cell Res.  2009 Aug 1;315(13):2231-40.
    --------------Review

26. Furumatsu T*, Ozaki T, Asahara H*. Smad3 activates the Sox9-dependent transcription on chromatin. Int J Biochem Cell Biol. 2009 May;41(5):1198-204. 

27. Shimizu H, Uchibe K, Asahara H*. Large-scale whole mount in situ hybridization of mouse embryos. Methods Mol Biol. (Chapter 13)   Human Press. 2009;577:167-79. Book. Review.
    ---------------------------Collaboration

28. Kato Y, Miyaki S, Yokoyama S, Omori S, Inoue A, Horiuchi M, Asahara H. Real-time functional imaging for monitoring miR-133 during myogenic differentiation. Int J Biochem Cell Biol. 2009 Nov;41(11):2225-31. 

29. Abe Y, Oka A, Mizuguchi M, Igarashi T, Ishikawa S, Aburatani H, Yokoyama S, Asahara H, Nagao K, Yamada M, Miyashita T. EYA4, deleted in a case with middle interhemispheric variant of holoprosencephaly, interacts with SIX3 both physically and functionally. Hum Mutat. 2009 Oct;30(10):E946-55.

30. Nagata Y, Nakasa T, Mochizuki Y, Ishikawa M, Miyaki S, Shibuya H, Yamasaki K, Adachi N, Asahara H, Ochi M. Induction of apoptosis in the synovium of mice with autoantibody-mediated arthritis by the intraarticular injection of double-stranded MicroRNA-15a. Arthritis Rheum. 2009 Sep;60(9):2677-83.

31. FANTOM Consortium, Suzuki H, Forrest AR, van Nimwegen E, Daub CO, Balwierz PJ, Irvine KM, Lassmann T, Ravasi T, Hasegawa Y, de Hoon MJ, Katayama S, Schroder K, Carninci P, Tomaru Y, Kanamori-Katayama M, Kubosaki A, Akalin A, Ando Y, Arner E, Asada M, Asahara H, Bailey T, Bajic VB, Bauer D, Beckhouse AG, Bertin N, Björkegren J, Brombacher F, Bulger E, Chalk AM, Chiba J, Cloonan N, Dawe A, Dostie J, Engström PG, Essack M, Faulkner GJ, Fink JL, Fredman D, Fujimori K, Furuno M, Gojobori T, Gough J, Grimmond SM, Gustafsson M, Hashimoto M, Hashimoto T, Hatakeyama M, Heinzel S, Hide W, Hofmann O, Hörnquist M, Huminiecki L, Ikeo K, Imamoto N, Inoue S, Inoue Y, Ishihara R, Iwayanagi T, Jacobsen A, Kaur M, Kawaji H, Kerr MC, Kimura R, Kimura S, Kimura Y, Kitano H, Koga H, Kojima T, Kondo S, Konno T, Krogh A, Kruger A, Kumar A, Lenhard B, Lennartsson A, Lindow M, Lizio M, Macpherson C, Maeda N, Maher CA, Maqungo M, Mar J, Matigian NA, Matsuda H, Mattick JS, Meier S, Miyamoto S, Miyamoto-Sato E, Nakabayashi K, Nakachi Y, Nakano M, Nygaard S, Okayama T, Okazaki Y, Okuda-Yabukami H, Orlando V, Otomo J, Pachkov M, Petrovsky N, Plessy C, Quackenbush J, Radovanovic A, Rehli M, Saito R, Sandelin A, Schmeier S, Schönbach C, Schwartz AS, Semple CA, Sera M, Severin J, Shirahige K, Simons C, St Laurent G, Suzuki M, Suzuki T, Sweet MJ, Taft RJ, Takeda S, Takenaka Y, Tan K, Taylor MS, Teasdale RD, Tegnér J, Teichmann S, Valen E, Wahlestedt C, Waki K, Waterhouse A, Wells CA, Winther O, Wu L, Yamaguchi K, Yanagawa H, Yasuda J, Zavolan M, Hume DA; Riken Omics Science Center, Arakawa T, Fukuda S, Imamura K, Kai C, Kaiho A, Kawashima T, Kawazu C, Kitazume Y, Kojima M, Miura H, Murakami K, Murata M, Ninomiya N, Nishiyori H, Noma S, Ogawa C, Sano T, Simon C, Tagami M, Takahashi Y, Kawai J, Hayashizaki Y. The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nat Genet. 2009 May;41(5):553-62.

32. Yamasaki K, Nakasa T, Miyaki S, Ishikawa M, Deie M, Adachi N, Yasunaga Y, Asahara H, Ochi M. Expression of MicroRNA-146a in osteoarthritis cartilage. Arthritis Rheum. 2009 Apr;60(4):1035-41.

33. Hikata T, Takaishi H, Takito J, Hakozaki A, Furukawa M, Uchikawa S, Kimura T, Okada Y, Matsumoto M, Yoshimura A, Nishimura R, Reddy SV, Asahara H, Toyama Y. PIAS3 negatively regulates RANKL-mediated osteoclastogenesis directly in osteoclast precursors and indirectly via osteoblasts. Blood. 2009 Mar 5;113(10):2202-1.

34. Kumagishi K, Nishida K, Yamaai T, Momota R, Miyaki S, Hirohata S, Naito I, Asahara H, Ninomiya Y, Ohtsuka A. A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) expression by chondrocytes during endochondral ossification. Arch Histol Cytol. 2009;72(3):175-85.

35. Grogan SP, Miyaki S, Asahara H, D'Lima DD, Lotz MK. Mesenchymal progenitor cell markers in human articular cartilage: normal distribution and changes in osteoarthritis.Arthritis Res Ther.  2009;11(3):R85.
    
    2008

36. Nakasa T, Miyaki S, Okubo A, Hashimoto M, Nishida K, Ochi M, Asahara H*. Expression of microRNA-146 in rheumatoid arthritis synovial tissue. Arthritis Rheum. 2008 May;58(5):1284-92.

37. Yokoyama S, Hashimoto M, Shimizu H, Ueno-Kudoh H, Uchibe K, Kimura I,  Asahara H*. Dynamic gene expression of Lin-28 during embryonic development in mouse and chicken. Gene Expr Patterns. 2008 Feb;8(3):155-60.
    --------------Review

38. Hashimoto M, Nakasa T, Hikata T, Asahara H*. Molecular  network of cartilage homeostasis and osteoarthritis. Med Res Rev. 2008 May;28(3):464-81. Review.

39. Yoshitaka T,  Asahara H* Epigenetics and Cartilage Regulation. US Musculoskeletal Review.  2008; 3(1): 45-47. Review.
    ---------------------------Collaboration

40. Sakai N, Terami H, Suzuki S, Haga M, Nomoto K, Tsuchida N, Morohashi K, Saito N, Asada M, Hashimoto M, Harada D, Asahara H, Ishikawa T, Shimada F, Sakurada K. Identification of NR5A1 (SF-1/AD4BP) gene expression modulators by large-scale gain and loss of function studies. J Endocrinol. 2008 Sep;198(3):489-97. 
    
    2007

41. Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H*. Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification. Mol Cell Biol. 2007 Aug;27(16):5650-63. 
    --------------Review

42. Shimizu H, Yokoyama S, Asahara H*. Growth and differentiation of the developing limb bud from the perspective of chondrogenesis. Dev Growth Differ. 2007 Aug;49(6):449-54.Review.
    
    2006

43. Sato K, Suematsu A, Nakashima T, Takemoto-Kimura S, Aoki K, Morishita Y, Asahara H, Ohya K, Yamaguchi A, Takai T, Kodama T, Chatila TA, Bito H, Takayanagi H. Regulation of osteoclast differentiation and function by the CaMK-CREB pathway. Nat Med. 2006 Dec;12(12):1410-6. E 
    
    2005

44. Furumatsu T, Tsuda M, Yoshida K, Taniguchi N, Ito T, Hashimoto M, Ito T, Asahara H*. Sox9 and p300 cooperatively regulate chromatin-mediated transcription. J Biol Chem. 2005 Oct 21;280(42):35203-8. 

45. Furumatsu T, Tsuda M, Taniguchi N, Tajima Y, Asahara H*. Smad3 induces chondrogenesis through the activation of SOX9 via CREB-binding protein/p300 recruitment. J Biol Chem. 2005 Mar 4;280(9):8343-50. 

46. Kawakami Y, Tsuda M, Takahashi S, Taniguchi N, Esteban CR, Zemmyo M, Furumatsu T, Lotz M, Izpisúa Belmonte JC,  Asahara H*.Transcriptional coactivator PGC-1alpha regulates chondrogenesis via association with Sox9. Proc Natl Acad Sci U S A. 2005 Feb 15;102(7):2414-9.  
    
    2004

47. Nishida K, Komiyama T, Miyazawa S, Shen ZN, Furumatsu T, Doi H, Yoshida A, Yamana J, Yamamura M, Ninomiya Y, Inoue H, Asahara H*.Histone deacetylase inhibitor suppression of autoantibody-mediated arthritis in mice via regulation of p16INK4a and p21(WAF1/Cip1) expression. Arthritis Rheum. 2004 Oct;50(10):3365-76.
    ---------------------------Collaboration

48. Omoto S, Nishida K, Yamaai Y, Shibahara M, Nishida T, Doi T, Asahara H, Nakanishi T, Inoue H, Takigawa M. Expression and localization of connective tissue growth factor (CTGF/Hcs24/CCN2) in osteoarthritic cartilage. Osteoarthritis Cartilage. 2004 Oct;12(10):771-8.

49. Kato T, Asahara H, Kurokawa MS, Fujisawa K, Hasunuma T, Inoue H, Tsuda M, Takahashi S, Motokawa S, Sumida T, Nishioka K. HTLV-I env protein acts as a major antigen in patients with HTLV-I-associated arthropathy. Clin Rheumatol. 2004 Oct;23(5):400-9.
    
    2003

50. Tsuda M, Takahashi S, Takahashi Y, Asahara H*.Transcriptional co-activators CREB-binding protein and p300 regulate chondrocyte-specific gene expression via association with Sox9.  J Biol Chem. 2003 Jul 18;278(29):27224-9.
    ---------------------------Collaboration

51. Kawakami Y, Rodríguez-León J, Koth CM, Büscher D, Itoh T, Raya A, Ng JK, Esteban CR, Takahashi S, Henrique D, Schwarz MF, Asahara H, Izpisúa Belmonte JC. MKP3 mediates the cellular response to FGF8 signalling in the vertebrate limb. Nat Cell Biol. 2003 Jun;5(6):513-9.

52. Canettieri G, Morantte I, Guzmán E, Asahara H, Herzig S, Anderson SD, Yates JR 3rd, Montminy M. Attenuation of a phosphorylation-dependent activator by an HDAC-PP1 complex.  Nat Struct Biol. 2003 Mar;10(3):175-81.
    
    2002

53. Asahara H, Tartare-Deckert S, Nakagawa T, Ikehara T, Hirose F, Hunter T, Ito T, Montminy M. Dual roles of p300 in chromatin assembly and transcriptional activation in cooperation with nucleosome assembly protein 1 in vitro. Mol Cell Biol. 2002 May;22(9):2974-83.
    
    2001

54. Xu W, Chen H, Du K, Asahara H, Tini M, Emerson BM, Montminy M, Evans RM. A transcriptional switch mediated by cofactor methylation. Science. 2001 Dec 21;294(5551):2507-11. 

55. Asahara H, Santoso B, Guzman E, Du K, Cole PA, Davidson I, Montminy M. Chromatin-dependent cooperativity between constitutive and inducible activation domains in CREB. Mol Cell Biol. 2001 Dec;21(23):7892-900.

56. Long F, Schipani E, Asahara H, Kronenberg H, Montminy M. The CREB family of activators is required for endochondral bone development. Development. 2001 Feb;128(4):541-50.

57. Sekine T, Masuko-Hongo K, Matsui T, Asahara H, Takigawa M, Nishioka K, Kato T.  Recognition of YKL-39, a human cartilage related protein, as a target antigen in patients with rheumatoid arthritis. Ann Rheum Dis. 2001 Jan;60(1):49-54.
    2000

58. Du K, Asahara H, Jhala US, Wagner BL, Montminy M. Characterization of a CREB gain-of-function mutant with constitutive transcriptional activity in vivo. Mol Cell Biol. 2000 Jun;20(12):4320-7.

59. Asaumi K, Nakanishi T, Asahara H, Inoue H, Takigawa M. Expression of neurotrophins and their receptors (TRK) during fracture healing. Bone. 2000 Jun;26(6):625-33.

60. Shibahara M, Nishida K, Asahara H, Yoshikawa T, Mitani S, Kondo Y, Inoue H. Increased osteocyte apoptosis during the development of femoral head osteonecrosis in spontaneously hypertensive rats. Acta Med Okayama. 2000 Apr;54(2):67-74.

61. Michael LF, Asahara H, Shulman AI, Kraus WL, Montminy M. The phosphorylation status of a cyclic AMP-responsive activator is modulated via a chromatin-dependent mechanism. Mol Cell Biol. 2000 Mar;20(5):1596-603. 
    
    1999

62. Asahara H, Dutta S, Kao HY, Evans RM, Montminy M. Pbx-Hox heterodimers recruit coactivator-corepressor complexes in an isoform-specific manner. Mol Cell Biol. 1999 Dec;19(12):8219-25.

63. Suzuki M, Asahara H, Endo S, Inada K, Doi M, Kuroda K, Ogawa A. Increased levels of nitrite/nitrate in the cerebrospinal fluid of patients with subarachnoid hemorrhage. Neurosurg Rev. 1999 Oct;22(2-3):96-8.

64. Maeda T, Keino H, Asahara H, Taniguchi M, Nishioka K, Sumida T. Decreased TCR AV24AJ18+ double-negative T cells in rheumatoid synovium.Rheumatology (Oxford).  1999 Feb;38(2):186-8. 
    
    1998

65. Okamoto K, Asahara H, Kobayashi T, Matsuno H, Hasunuma T, Kobata T, Sumida T, Nishioka K. Induction of apoptosis in the rheumatoid synovium by Fas ligand gene transfer. Gene Ther. 1998 Mar;5(3):331-8.

66. Takagoshi H, Hashizume H, Nishida K, Masaoka S, Asahara H, Inoue H. Fibrous structure and connection surrounding the metacarpophalangeal joint. Acta Med Okayama. 1998 Feb;52(1):19-26.

67. Pu J, Nishida K, Inoue H, Asahara H, Ohtsuka A, Murakami T. Mast cells in osteoarthritic and rheumatoid arthritic synovial tissues of the human knee. Acta Med Okayama. 1998 Feb;52(1):35-9.

68. Sumida T, Hasunuma T, Asahara H, Maeda T, Nishioka K. Rheumatoid arthritis and apoptosis. Intern Med. 1998 Feb;37(2):184-8. Review.

69. Fujisawa K, Okamoto K,  Asahara H, Hasunuma T, Kobata T, Kato T, Sumida T, Nishioka K. Evidence for autoantigens of Env/Tax proteins in human T cell leukemia virus type I Env-pX transgenic mice. Arthritis Rheum.1998 Jan;41(1):101-9.
    
    1997

70. Kobata T, Takasaki K, Asahara H, Hong NM, Masuko-Hongo K, Kato T, Hirose S, Shirai T, Kayagaki N, Yagita H, Okumura K, Nishioka K. Apoptosis with FasL+ cell infiltration in the periphery and thymus of corrected autoimmune mice. Immunology. 1997 Oct;92(2):206-13. 

71. Xue C, Hasunuma T, Asahara H, Yin W, Maeda T, Fujisawa K, Dong Y, Sumida T, Nishioka K. Transcriptional regulation of the HOX4C gene by basic fibroblast growth factor on rheumatoid synovial fibroblasts. Arthritis Rheum. 1997 Sep;40(9):1628-35.

72. Asahara H, Fujisawa K, Kobata T, Hasunuma T, Maeda T, Asanuma M, Ogawa N, Inoue H, Sumida T, Nishioka K. Direct evidence of high DNA binding activity of transcription factor AP-1 in rheumatoid arthritis synovium. Arthritis Rheum. 1997 May;40(5):912-8.

73. Suzuki M, Ogawa A, Asahara H, Endo S, Inada K. Nitric oxide and vasospasm. J Neurosurg. 1997 Apr;86(4):741-2.

74. Asahara H, Hasunuma T, Kobata T, Inoue H, Muller-Ladner U, Gay S, Sumida T, Nishioka K. In situ expression of protooncogenes and Fas/Fas ligand in rheumatoid arthritis synovium. J Rheumatol. 1997 Mar;24(3):430-5.

75. Sumida T, Hoa TT, Asahara H, Hasunuma T, Nishioka K. T cell receptor of Fas-sensitive T cells in rheumatoid synovium. J Immunol. 1997 Feb 15;158(4):1965-70.

76. Hasunuma T, Kayagaki N, Asahara H, Motokawa S, Kobata T, Yagita H, Aono H, Sumida T, Okumura K, Nishioka K. Accumulation of soluble Fas in inflamed joints of patients with rheumatoid arthritis. Arthritis Rheum. 1997 Jan;40(1):80-6.

77. Yokoi I, Kabuto H, Habu H, Inada K, Toma J, Asahara H, Mori A. Structure-activity relationships of guanidine compounds on brain nitric oxide synthase activity. Guanidino Compounds: 2, eds. By P.P. De Deyn, B. Marescau, I.A. Qureshi, A. Mori. John Libbey & Company Ltd. 1997: 3-7. Review. Book.

78. 
    .Habu H, Yokoi I, Kabuto H,Asahara H, Toma J, Inada K, Mori A.The role of nitric oxide on α-guanidinoglutaric acid induced epileptic discharges.Guanidino Compounds: 2, eds. By P.P. De Deyn, B. Marescau, I. A. Qureshi, A. Mori. John Libbey & Company Ltd. 1997: 373-377. Review. Book
    
    1996

79. Hasunuma T, Hoa TT, Aono H, Asahara H, Yonehara S, Yamamoto K, Sumida T, Gay S, Nishioka K. Induction of Fas-dependent apoptosis in synovial infiltrating cells in rheumatoid arthritis. Int Immunol. 1996 Oct;8(10):1595-602.

80. Asahara H, Hasumuna T, Kobata T, Yagita H, Okumura K, Inoue H, Gay S, Sumida T, Nishioka K. Expression of Fas antigen and Fas ligand in the rheumatoid synovial tissue. Clin Immunol Immunopathol. 1996 Oct;81(1):27-34.

81. Fujisawa K, Asahara H, Okamoto K, Aono H, Hasunuma T, Kobata T, Iwakura Y, Yonehara S, Sumida T, Nishioka K. Therapeutic effect of the anti-Fas antibody on arthritis in HTLV-1 tax transgenic mice. J Clin Invest. 1996 Jul 15;98(2):271-8.

82. Asahara H, Kawai A, Harada Y, Senda M, Inoue H. Spinal schwannomas: a review of 42 cases. Acta Med Okayama. 1996 Feb;50(1):25-8.

83. Hashizume H, Asahara H, Nishida K, Inoue H, Konishiike T. Histopathology of Kienböck's disease. Correlation with magnetic resonance and other imaging techniques. J Hand Surg Br. 1996 Feb;21(1):89-93.

84. Asahara H, Yokoi I, Tamada T, Kabuto H, Ogawab N, Mori A, Inoue H. Increased cerebrospinal fluid nitrite and nitrate levels in patients with lumbar spondylosis. Res Commun Mol Pathol Pharmacol. 1996 Jan;91(1):77-83.
    
    1995

85. Asahara H, Asanuma M, Ogawa N, Nishibayashi S, Inoue H. High DNA-binding activity of transcription factor NF-kappa B in synovial membranes of patients with rheumatoid arthritis. Biochem Mol Biol Int. 1995 Nov;37(5):827-32.

86. Asahara H, Kabuto H, Yokoi I, Habu H, Mori A, Inoue H. Nitric oxide synthase inhibited by audouine  in the rat brain. Neuroreport. 1995 May 30;6(8):1146-8.

87. Kabuto H, Yokoi I, Habu H, Asahara H, Mori A. Inhibitory effect of arcaine on nitric oxide synthase in the rat brain. Neuroreport. 1995 Feb 15;6(3):554-6. 

​

   Top